Encuesta sobre diferimiento del donante de sangre por anemia: Predictores y estrategias desarrolladas para las posteriores donaciones.

Autores

César Cerdas-Quesada

RESUMEN

Los donantes habituales de sangre corren el riesgo de sufrir deficiencia de hierro, pero las características que predisponen a esta afección no están bien definidas. La deficiencia de hierro prevalece en las poblaciones de donantes de sangre donde hasta el 39%, el 22% y el 9% de las mujeres premenopáusicas que donan con frecuencia, las mujeres posmenopáusicas y los hombres pueden tener deficiencia de hierro, respectivamente. Se envió al donante posterior a las visitas a sus centros de trabajo o estudio (centros de donación extramurales) vía correo electrónico entre junio de 2017 y enero de 2018. Se enviaron 876 correos electrónicos a donantes de las colectas externas del Banco de Sangre del Hospital La Católica llevadas a cabo en 23 empresas, de las cuales se completaron 476 encuestas. El diferimiento por anemia entre los donantes fue del 6% y los factores asociados a estos donantes incluyeron alta frecuencia de donación, sexo, consumo de tabletas de hierro y dietas restrictivas. La deficiencia de hierro es un problema importante y es necesario realizar más estudios para medir los depósitos de hierro y valorar la ampliación del intervalo entre donaciones de sangre y el uso de suplementos para potenciar la recuperación de los depósitos.

Palabras clave

Donantes voluntarios de sangre, deficiencia de hierro, nivel dehemoglobina, encuesta de donantes de sangre

ABSTRACT

Regular blood donors are at risk of iron deficiency but characteristics that predispose to this condition are poorly defined. Iron deficiency is prevalent in blood donor populations where up to 39%, 22% and 9% of frequently donating premenopausal women, postmenopausal women and men may be iron-deficient, respectively. The survey was sent to the donor after the donation at their work or study centers (extramural donation centers) via email between June 2017 and January 2018. 876 emails were sent to donors of the Blood Bank of the Hospital La Catolica carried out in 23 companies, of which 476 surveys were completed. Deferred anemia among donors was 6% and the factors associated with these donors included high frequency of donation, sex, consumption of iron tablets and consumption of meat. Iron deficiency is a major problem and further studies are needed to measure iron stores and the increase of the interval between blood donations and the use of supplements to enhance the recovery of deposits.

Keywords

Regular blood donors are at risk for iron deficiency, but characteristics that predispose this condition are not well defined. Iron deficiency prevails in blood donor populations
Zeger G, Selogie E, Shulman I. Blood Donation and Collection. En: Hillyer et al, 2nd ed. Blood Banking and transfusion medicine: Basic principles and practice. Livingstone Elsevier 2007:157-182. Baart M, Vergouwe Y, Atsma F, Moons K, deKorr L. Prediction of hemoglobin levels in whole blood donors: how to model donation history. Transfusion 2014;54:925-932. Vuk T, Magnussen K, de Kort W, Follea G, Liumbruno G, et al. International Forum: an investigation of iron status in blood donors. Blood Transfus 2017,15:20-41. Mendrome A, Cerdetra E, Sampado L, Almeida C, Schreiber G, Fischer D, Dorlhiac P. Anemia screening in potential female blood donors: comparison of two different quantitative methods. Transfusion 2009;49:662-668. Gongora Falero G, Díaz D, Mazzieri O, Canle O. Evaluación de un programa de donación de sangre altruista y habitual gestionado por colectas externas. Revista Argentina de Transfusión 2011;36:309-317. Beutler E, Waalen J. The definition of anemia: what is the lower limit of normal of the blood hemoglobin concentration? Blood 2006;107:1747-1750. Tong E, Murphy WG, Kinsella A, Darragh E, Woods J, Murphy C, et al. Capillary and venous haemoglobi levels in blood donors: a 42-month study of 36258 paired samples. Vox Sang 2010;98:547-553. Ziemann M, Lizardo B, Geusendam G, Schlenke P. Reliability of capillary hemoglobin screening under routine conditions. Transfusion 2011,51:2714-2719. Bryant BJ, Yau YY, Arceo SM, Niel-Johnson J, Hopkins JA, Leitman SF. Iron replacement therapy in the routine management of blood donors. Transfusion 2012:52:1566-1575. Glynn S, Schreiber G, Murphy E, Kessler D, Higgins M, Wright D, et al. Factors influencing the decision to donate: racial and ethnic comparisons. Transfusion 2006;46:980-90. Misje A, Bosnes V, Gasdal O, Heier H. Motivation, recruitment and retention of voluntary nonremunerated blood donors: a Survey-based questionnaire study. Vox sang 2005;89:236-44. Schreider G, Schlumpf K, Glynn S, Wrigth D, Tu Y, King M et al. Convenience the bane of our existente, and other barriers to donating. Transfusion 2006;46:545-53. Davey R. The blood center as a community health resource. Vox Sang 2006;91:206-13. Eason S, Goudar S, Centilli J, Sayers M. Experience with routine total nonfasting blood colesterol screening of volunteer blood and component donors. Transfusion 2011;51:731-6. Codigo Etico aprobado en la Asamblea General de Copenhague, Junio 2017. www.isbtweb.org Rigas AS, Sorensen CJ, Pedersen OB, Petersen MS, Thorner LW, Kotze S, Sorensen E, Magnussen K, Rostgaard K, Erikstrup C, Ullum H. Predictors of iron levels in 14,737 Danish blood donors: results from the Danish Blood Donor Study. Transfusion 2014,54:789-796. Cable RG, Glynn SA, Kiss JE, Mast AE, Steele WR, Murphy EL, Wrigth DJ,Sacher RA, Gottschall JL, Vij V, Simon TL. Iron deficiency in blood donors: analysis of enrollment data from the REDS-II Donor Iron Status Evaluation (RISE) study. Transfusion 2011;51:511-22 Standards for Blood Banks and Transfusion Services, 30th edition, American Association of Blood Banks and Cellular Therapies Worldwide 2016. A. S. Rigas, O. B. Pedersen, C. Erikstrup, H. Hjalgrim, H. Ullum, Blood donation and iron deficiency, ISBT Science Series, 2017;2:142-147. Booth AO, Lim K, Capper H, Irving D, Fisher J, McNaughton SA, Roddell L, Keller A, Nowson CA. Iron status and dietary iron intake of female blood donors. Transfusion 2014;54:770-774. Marks D, Speedy J, Robinsos K, Brama T, Capper H, Mondy P, Keller A. An 8-week course of 45 mg of carbonyl iron daily reduces iron deficiency in females whole blood donors aged 18 to 45 years: results of a prospective randomized controlled trial. Transfusion 2014;54:780-788. Dalaney M, Schellhase KG, Young Staci, Geiger S, Fink A, Mast AE. Blood center practice and education for blood donors with anemia. Transfusion 2011;51:929-936.