Virus Epstein Barr: primer oncovirus humano descubierto y su relación con el desarrollo de enfermedades hematooncológicas como el Linfoma de Burkitt.
Autores
Luisa Alejandra Vindas-Angulo
Resumen
El descubrimiento de la relación entre procesos infecciosos virales y el desarrollo de enfermedades oncológicas tiene más de un siglo de conocerse. Al inicio estos sólo fueron de interés para elucidar enfermedades que afectaban animales domésticos; sin embargo con el paso de los años se realizaron otras investigaciones que buscaban atribuirle un origen infeccioso a cierto tipos de cáncer en humanos. El virus del Epstein Barr es un oncovirus y su asociación con el Linfoma de Burkitt fue descubierta casi al mismo momento en el que este fue descrito por primera vez. Los genes que permiten la latencia de Epstein Barr son los principalmente relacionados con el desarrollo de ésta y otras patologías hematooncológicas.
Palabras clave
Oncovirus, Epstein Barr, oncogenes, linfoma de BurkittAbstract
The discovery of the relationship between viral infectious processes and the development of oncological diseases has been known for more than a century. At first, these were only of interest for elucidating diseases affecting domestic animals; however, over the years, other research was carried out that sought to attribute an infectious origin to certain types of cancer in humans. The Epstein Barr virus is an oncovirus and its association with Burkitt’s lymphoma was discovered at about the same time it was first described. The genes that allow the latency of Epstein Barr are those mainly related to the development of this and other hematooncological pathologies.
Key words
Oncovirus, Epstein Barr, oncogenes, Burkitt's lymphomaTexto completo
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